Injectible Fillers

In Denver our active population stays fit but spends lots of time outdoors in the sun enjoying our weather.  This leads to premature aging with fine lines, wrinkles, and creases.  As the face ages, it develops further wrinkling and volume loss.  These aging-related changes can respond nicely to the injection of filler material. 

Soft Tissue Fillers - Dermal fillers are generally created from naturally occurring substances: Hyaluronic acid (HA), Calcium hydroxylapatite (Radiesse™), and Poly-L-lactic acid (Sculptra™.)  These substances either bind moisture to plump up lines and wrinkles or they leave behind collagen to add volume to the skin.  Our surgeons will inject these substances at varying depths within the skin to fill facial imperfections such as creases, scars, and wrinkles.  Fillers are also used to enhance the volume and define the shape of the lips, cheeks, chin, jawline, and hands.  At the Center for Plastic and Aesthetic Surgery in Denver, Colorado, our surgeons choose to inject their patients with the following dermal fillers:

  • Juvederm™(Ultra and Ultra Plus): FDA-approved in June 2006, Juvederm™ treats mild to moderate facial creases (such as the "parenthesis" on either side of your mouth.) Juvederm™ also smoothes and softens the appearance of scars and other depressed areas and plumps and defines the lips.  One treatment with Juvederm™ lasts up to one year.
  • Radiesse™: FDA-approved in December 2006, Radiesse™ treats mild to moderate facial creases and wrinkles around the nose and mouth.  Comparable to Juvederm™, a single treatment with Radiesse™ lasts up to eighteen months.
  • Restylane™: FDA-approved in December 2003, Restylane™ treats mild to moderate facial creases, replacing lost volume and smoothing wrinkles.  This product is comparable to Juvederm™, and one treatment lasts six to eight months.
  • Perlane™ (Restylane™ family): FDA-approved in May 2007, Perlane™ treats moderate facial creases and is designed for deeper injection than Juvederm™ and traditional Restylane™.  One treatment with Perlane™ lasts at least six to eight months in most patients.
  • Sculptra™: FDA-approved in August 2004, Sculptra™ was originally intended to treat lipoatrophy (loss of facial fat) in HIV-positive individuals.  Our surgeons also use Sculptra™ in non-HIV individuals to add volume to facial features.  One treatment of Sculptra™ should last about two years.  It generally takes three to four treatments for full correction.
  • Evolence™: FDA-approved in June 2008, Evolence is a collagen product that has a one year duration in studies.  It is a soft, natural-feeling filler that can be used to fill fine lines and wrinkles.  Because this collagen is more like human collagen than traditional collagen filler, it does not need pre-testing for allergies to collagen.


Juvederm™ XC (with Lidocaine) and new offerings from Mentor in the Prevelle™ line.  Stay tuned!


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Dr. Gregory A. Buford
“Be Beautiful…Look Like Yourself…Only Better”

Denver Plastic Surgeon, New You Plastic Surgery is a group of medical professionals dedicated to excellence in plastic and Aesthetic surgery such as Reconstructive Sugery, Breast Augmentation, Rhinoplasty, Face Lift, Tummy Tuck and more.

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